Migraines pill about.

Women who have migraines with visual problems have increased risk for heart disease, according to a study published on Wednesday in the Journal of the American Medical Association, Long Island Newsday reports. For the study, researchers at the Harvard School of Public Health and Brigham and Women’s Hospital analyzed the records of 27,800 women older than age 45 who participated in the Women’s Health Initiative. None of the women had heart disease when they entered the study between 1992 and 1995. Researchers focused on the records of 5,125 women who had a history of migraines. According to the study, participants who had migraines with migraine aura had more than twice the normal risk for major cardiovascular events. Migraine aura “is a visual sensation — like lights flashing or lines zigzagging, with some reports of temporary blindness” — that often lasts for 20 minutes to one hour before migraines begin, Newsday reports. Women who had migraines without migraine aura did not have an increased risk for major cardiovascular events, the study finds. Lead study author Tobias Kurth said that researchers did not determine the cause of the link between migraine aura and heart disease and that the increased risk was small, with about 18 additional cases of heart disease per 10,000 women with migraine aura. Mark Gudesblatt, a neurologist at South Shore Neurologic Associates, said, “It’s an important study because it tells you not to take these things lightly” (Talan, Long Island Newsday, 7/19).

Study Authors Did Not Report Financial Ties

The six authors of the study did not disclose to JAMA that they have consulted for, or received research funds from, pharmaceutical companies that manufacture treatments for heart disease or migraines, the AP/Miami Herald reports. JAMA in January implemented a policy that requires financial disclosures from researchers before acceptance of studies for publication, and an editorial published in the journal last week indicated that “JAMA was getting tougher as a result of … recent breaches” of the policy, the AP/Herald reports. JAMA Editor in Chief Catherine DeAngelis said that journal editors were not aware of the financial ties until the Associated Press informed her about them last week. The authors said they did not report the financial ties because the study does not promote a treatment. JAMA on Tuesday published online a letter from the authors of the study to explain their failure to disclose the financial ties, as well as a response from DeAngelis and a correction. DeAngelis said that the letter, her response and the correction will appear in a future print edition of JAMA. “Let me decide what’s pertinent or not,” DeAngelis said, adding, “Authors should always err on the side of full disclosure.” Kurth in an interview said that the financial ties “do not represent a conflict of interest” (Tanner, AP/Miami Herald, 7/19).